Three decades of innovation in the management of sickle cell disease: the road to understanding the sickle cell disease clinical phenotype.

Abstract excerpt

In the United States, sickle cell disease affects approximately 1 in 350 African-American newborn infants each year, and approximately 72,000 individuals total. Sickle cell disease is the most prevalent genetic hematologic disorder in the US. In 1972, the National Sickle Cell Disease Control Act was passed by Congress. This landmark piece of legislation established the National Sickle Cell Disease Program which...

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