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Article

Sickle cell disease: a malady beyond a hemoglobin defect in cerebrovascular disease.

Expert review of hematology - 1 Jan 2018

Ansari Junaid, Moufarrej Youmna E, Pawlinski Rafal, Gavins Felicity N E

Abstract excerpt

INTRODUCTION: Sickle cell disease (SCD) is a devastating monogenic disorder that presents as a multisystem illness and affects approximately 100,000 individuals in the United States alone. SCD management largely focuses on primary prevention, symptomatic treatment and targeting of hemoglobin polymerization and red blood cell sickling. Areas covered: This review will discuss the progress of SCD over the last few...

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Identifiers

PMID: 29207881
DOI: 10.1080/17474086.2018.1407240
PMCID: PMC6117162

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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