Article
Genome editing reveals the function of Yorkie during the embryonic and early larval development in silkworm, Bombyx mori.
Insect molecular biology - 1 Dec 2018
Xu X, Zhang Z, Yang Y, Huang S, Li K, He L, Zhou X
Abstract excerpt
As a transcriptional coactivator, Yorkie (Yki) is a major downstream target of the Hippo signalling pathway to regulate the organ size during animal development and regeneration. Previous microarray analysis in the silkworm, Bombyx mori, has shown that genes associated with the Hippo pathway were primarily expressed in gonads and imaginal discs. The RNA-interference-mediated silencing of Yki at the early...
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