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Label-Free Optical Marker for Red-Blood-Cell Phenotyping of Inherited Anemias.

Analytical chemistry - 19 Jun 2018

Mugnano Martina, Memmolo Pasquale, Miccio Lisa, Merola Francesco, Bianco Vittorio, Bramanti Alessia, Gambale Antonella, Russo Roberta, Andolfo Immacolata, Iolascon Achille, Ferraro Pietro

Abstract excerpt

The gold-standard methods for anemia diagnosis are complete blood counts and peripheral-smear observations. However, these do not allow for a complete differential diagnosis as that requires biochemical assays, which are label-dependent techniques. On the other hand, recent studies focus on label-free quantitative phase imaging (QPI) of blood samples to investigate blood diseases by using video-based...

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PMID: 29792684
DOI: 10.1021/acs.analchem.8b01076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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