Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dendrimers for gene delivery – a potential approach for ocular therapy?

19 Jul 2013

Abstract excerpt

OBJECTIVES: A vast number of blinding diseases have genetic aetiologies and may be treated by molecular based therapies such as antisense oligonucleotides or short interfering RNA. However, treatment success of ocular gene therapy is highly dependent on efficient delivery of such molecules. KEY FINDINGS: The majority of clinical studies for ocular gene therapy utilize viral vectors. While these have proven highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal Surgery and Treatments
Share to RNA Interference and Gene Delivery

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24635556
DOI: 10.1111/jphp.12104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dendrimers for gene delivery – a potential approach for ocular therapy?PMID 24635556Read ↗

The Role of Gene Therapy in the Treatment of Retinal Diseases: A ReviewSemantic proximity Read ↗

Ocular Gene Therapy: A Literature Review With Focus on Current Clinical TrialsSemantic proximity Read ↗

Are PAMAM dendrimers safe for ocular applications? -- Toxicological evaluation in ocular cells and intraocular tissuesSemantic proximity Read ↗

Ocular Gene Therapy: An Overview of Viral Vectors, Immune Responses, and Future DirectionsSemantic proximity Read ↗

Non-viral gene therapy for Leber’s congenital amaurosis: progress and possibilitiesSemantic proximity Read ↗

Gene therapy for ocular disease.Semantic proximity Read ↗

Gene therapy for inherited retinal diseases: exploiting new tools in genome editing and nanotechnologySemantic proximity Read ↗

Gene therapy strategies in ophthalmology—an overview of current developments and future prospectsSemantic proximity Read ↗

Gene Therapy Intervention in Neovascular Eye Disease: A Recent UpdateSemantic proximity Read ↗

AAV and Compacted DNA Nanoparticles for the Treatment of Retinal Disorders: Challenges and Future ProspectsSemantic proximity Read ↗

Has retinal gene therapy come of age? From bench to bedside and back to benchSemantic proximity Read ↗

Gene Delivery in the Cornea: In Vitro & Ex Vivo Evaluation of Solid Lipid Nanoparticle-Based VectorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.