Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1

1 May 2018

Abstract excerpt

How artificial environmental cues are biologically integrated and transgenerationally inherited is still poorly understood. Here, we investigate the mechanisms of inheritance of reproductive outcomes elicited by the model environmental chemical Bisphenol A in C. elegans. We show that Bisphenol A (BPA) exposure causes the derepression of an epigenomically silenced transgene in the germline for 5 generations,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Epigenetics and DNA Methylation
Share to Genetics, Aging, and Longevity in Model Organisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29791850
DOI: 10.1016/j.celrep.2018.04.078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1PMID 29791850Read ↗

Caenorhabditis Elegans as a Model for Environmental EpigeneticsSemantic proximity Read ↗

Endocrine-disrupting chemicals (EDCs) and epigenetic regulation in embryonic development: Mechanisms, impacts, and emerging trendsSemantic proximity Read ↗

A systems biology analysis of reproductive toxicity effects induced by multigenerational exposure to ionizing radiation in C. elegansSemantic proximity Read ↗

Reproductive Toxicity and Multi/Transgenerational Effects of Emerging Pollutants on C. elegansSemantic proximity Read ↗

Bridging the transgenerational gap with epigenetic memory.Semantic proximity Read ↗

Bisphenol TMC disturbs mitochondrial activity and biogenesis, reducing lifespan and healthspan in the nematode <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Mutation of C. elegans demethylase spr-5 extends transgenerational longevity.Semantic proximity Read ↗

Exposure to benzyl butyl phthalate (BBP) leads to increased double-strand break formation and germline dysfunction in Caenorhabditis elegansSemantic proximity Read ↗

Cadmium exposure induces multigenerational inheritance of germ cell apoptosis and fertility suppression in Caenorhabditis elegansSemantic proximity Read ↗

Chronic MeHg exposure modifies the histone H3K4me3 epigenetic landscape in Caenorhabditis elegansSemantic proximity Read ↗

The <i>C. elegans</i> SET-2 histone methyltransferase maintains germline fate by preventing progressive transcriptomic deregulation across generationsSemantic proximity Read ↗

AMX-1 is necessary for proper fertility and lack of its expression induced sterility in a p53/CEP-1 dependent manner by modulating piwi expression in C. elegansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.