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The Role of Interleukin-31 Polymorphisms in Non-Small Cell Lung Cancer Genetic Susceptibility and Clinical Outcome.

Genetic testing and molecular biomarkers - 1 May 2018

Yang Yongfeng, Li Li, Chen Fei, Zhang Li, Bu Hong

Abstract excerpt

BACKGROUND: Interleukin-31 (IL-31), a novel T helper type 2 effector cytokine, is known to have an important effect on the pathogenesis of allergic disease and tumors. However, the impact of IL-31 on human lung cancer remains unclear. METHODS: This study explored the role of IL-31 polymorphisms in lung cancer and sought to characterize how IL-31 polymorphisms correlate with lung cancer tumorigenesis and patient...

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Identifiers

PMID: 29791232
DOI: 10.1089/gtmb.2017.0256

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