Article
Polymorphisms and expression of IL-32: impact on genetic susceptibility and clinical outcome of lung cancer.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2017
Wang Yanwen, Yang Yongfeng, Zhu Yihan, Li Li, Chen Fei, Zhang Li
Abstract excerpt
CONTEXT: Polymorphisms of IL-32 related closely to tumoregenesis. MATERIALS AND METHODS: Two IL-32 polymorphisms (rs12934561 and rs28372698) and mRNA expression were conducted by SNP genotype assay and real-time PCR in 423 lung cancer patients and 437 controls. RESULTS: T allele of rs28372698 associated significantly with poor prognosis in moderate and well-differentiated lung cancer patients. TT genotype of...
Read the complete abstract on PubMed