Article
Clinical significance of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 gene polymorphisms in patients with gastrointestinal stromal tumors.
Asia-Pacific journal of clinical oncology - 1 Jun 2014
Kang Byung Woog, Kim Jong Gwang, Chae Yee Soo, Bae Han Ik, Kwon Ohkyoung, Chung Ho Young, Yu Wansik, Song Hong Suk, Kang Yu Na, Ryu Seung Wan, Lee Kyung Hee, Bae Young Kyung, Choi Joon Hyuk, Kim Se Won, Ryoo Hun-Mo, Cho Chang-Ho, Chae Hyun-Dong, Park Kyun Woo, Gu Mi Jin, Bae Byung-Jo
Abstract excerpt
AIM: The vascular endothelial growth factor (VEGF) or its family might play role in tumor-related angiogenesis in gastrointestinal stromal tumors (GIST), thereby affecting the prognosis. Accordingly, the present study analyzed the impact of VEGF and VEGF receptor-2 (VEGFR-2) gene polymorphisms on the prognosis for GIST patients. METHODS: In all, 213 consecutive patients with GIST from five medical centers were...
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