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Article

Genotype-phenotype links in frontotemporal lobar degeneration.

Nature reviews. Neurology - 1 Jun 2018

Van Mossevelde Sara, Engelborghs Sebastiaan, van der Zee Julie, Van Broeckhoven Christine

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) represents a group of neurodegenerative brain diseases with highly heterogeneous clinical, neuropathological and genetic characteristics. This high degree of heterogeneity results from the presence of several different underlying molecular disease processes; consequently, it is unlikely that all patients with FTLD will benefit from a single therapy. Therapeutic strategies...

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Identifiers

PMID: 29777184
DOI: 10.1038/s41582-018-0009-8

Genes

GRN
TBK1
VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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