Article
Effect of abnormal activated B cells in patients with ankylosing spondylitis and its molecular mechanism.
European review for medical and pharmacological sciences - 1 May 2018
Ge L, Wang J, Zhu B-Q, Zhang Z-S
Abstract excerpt
OBJECTIVE: Ankylosing spondylitis (AS) is a common clinical autoimmune disease, the pathogenesis of which, however, is not yet elucidated. In this study, we aim to explore the effect of B cells in the development and progression of AS and its underlying mechanism. PATIENTS AND METHODS: B cells were isolated from peripheral blood of AS patients and normal controls. Surface expression of CD40 in B cells was...
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