Article
Identification of a Recurrent LMO7-BRAF Fusion in Papillary Thyroid Carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Jun 2018
He Huiling, Li Wei, Yan Pearlly, Bundschuh Ralf, Killian Jackson A, Labanowska Jadwiga, Brock Pamela, Shen Rulong, Heerema Nyla A, de la Chapelle Albert
Abstract excerpt
BACKGROUND: The BRAFV600E mutation is the most common driver in papillary thyroid carcinoma (PTC) tumors. In recent years, gene fusions have also been recognized as important drivers of cancer in PTC. Previous studies have suggested that thyroid tumors with fusion genes frequently display an aggressive course. These observations prompted further exploration of gene fusions in PTC tumors. The aim was to search for...
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