Article
PD-L1 mRNA expression in EGFR-mutant lung adenocarcinoma.
Oncology reports - 1 Jul 2018
Isobe Kazutoshi, Kakimoto Atsushi, Mikami Tetuo, Kaburaki Kyohei, Kobayashi Hiroshi, Yoshizawa Takahiro, Nakano Yuta, Makino Takashi, Otsuka Hajime, Sano Go, Sugino Keishi, Sakamoto Susumu, Takai Yujiro, Tochigi Naobumi, Iyoda Akira, Homma Sakae
Abstract excerpt
Molecular mechanisms of programmed death-ligand 1 (PD-L1) mRNA expression and roles of apoptosis and biomarkers are poorly understood in epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma patients. Thirty-three patients with recurrent postoperative EGFR-mutant lung adenocarcinoma (exon 19 deletion in 16, L858R in 15, G719C in 2 patients) treated with gefitinib were studied. PD-L1 mRNA expression...
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