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Article

Association of BIM Deletion Polymorphism and BIM-γ RNA Expression in NSCLC with EGFR Mutation.

Cancer genomics & proteomics - 1 Jan 2000

Isobe Kazutoshi, Kakimoto Atsushi, Mikami Tetsuo, Kaburaki Kyohei, Kobayashi Hiroshi, Yoshizawa Takahiro, Makino Takashi, Otsuka Hajime, Sano G O, Sugino Keishi, Sakamoto Susumu, Takai Yujiro, Tochigi Naobumi, Iyoda Akira, Homma Sakae

Abstract excerpt

AIM: This pilot study assessed the association of BIM deletion polymorphism and BIM RNA isoform in patients with EGFR-positive non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: The study included 33 patients with EGFR-positive NSCLC treated with gefitinib. BIM deletion polymorphism and BIM RNA isoform (EL/L/S/γ) were determined by polymerase chain reaction (PCR). RESULTS: BIM-γ expression was...

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Identifiers

PMID: 27807070
DOI: 10.21873/cgp.20010
PMCID: PMC5219921

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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