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Article

Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A

27 Jun 2018

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29758285
DOI: 10.1016/j.jid.2018.04.032

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Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type APMID 29758285Read ↗

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Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in MiceSemantic proximity Read ↗

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptensSemantic proximity Read ↗

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Acral Peeling Skin Syndrome with TGM5 Gene Mutations May Resemble Epidermolysis Bullosa Simplex in Young IndividualsSemantic proximity Read ↗

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Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads.Semantic proximity Read ↗

Murine filaggrin‐2 is involved in epithelial barrier function and down‐regulated in metabolically induced skin barrier dysfunctionSemantic proximity Read ↗

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