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Autophagy, cell death, and cancer

26 Jan 2015

Abstract excerpt

Autophagy is an evolutionarily conserved intracellular catabolic process that is used by all cells to degrade dysfunctional or unnecessary cytoplasmic components through delivery to the lysosome. Increasing evidence reveals that autophagic dysfunction is associated with human diseases, such as cancer. Paradoxically, although autophagy is well recognized as a cell survival process that promotes tumor development,...

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Identifiers

PMID: 27308466
DOI: 10.4161/23723556.2014.985913

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