Article
Acceleration of diabetic wound healing with adipose-derived stem cells, endothelial-differentiated stem cells, and topical conditioned medium therapy in a swine model.
Journal of vascular surgery - 1 Dec 2018
Irons Robin F, Cahill Kevin W, Rattigan Deviney A, Marcotte Joseph H, Fromer Marc W, Chang Shaohua, Zhang Ping, Behling Eric M, Behling Kathryn C, Caputo Francis J
Abstract excerpt
OBJECTIVE: The purpose of our study was to investigate the effect of adipose-derived stem cells (ASCs), endothelial-differentiated ASCs (EC/ASCs), and various conditioned media (CM) on wound healing in a diabetic swine model. We hypothesized that ASC-based therapies would accelerate wound healing. METHODS: Diabetes was induced in four Yorkshire swine through intravenous injection of streptozotocin. ASCs were...
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