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Article

VAP-PLGA microspheres (VAP-PLGA) promote adipose-derived stem cells (ADSCs)-induced wound healing in chronic skin ulcers in mice via PI3K/Akt/HIF-1α pathway.

Bioengineered - 1 Dec 2021

Jiang Wen, Zhang Jun, Zhang Xudong, Fan Chenghong, Huang Jinlong

Abstract excerpt

Chronic skin ulcers are a primary global health problem. Velvet antler polypeptide (VAP) regulates endothelial cell migration and angiogenic sprout. Adipose-derived stem cells (ADSCs) are reported to make pivotal impacts upon wound healing. This study aimed to explore the role of VAP combined with ADSCs in wound healing of chronic skin ulcers. The effect of VAP on phenotypes of ADSCs, and VAP (PLGA microspheres)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34720043
DOI: 10.1080/21655979.2021.1990193
PMCID: PMC8810082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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