Article
Structural and functional heterogeneity of cytochrome c oxidase in S. cerevisiae.
Biochimica et biophysica acta. Bioenergetics - 1 Sept 2018
Schäfer Jacob, Dawitz Hannah, Ott Martin, Ädelroth Pia, Brzezinski Peter
Abstract excerpt
Respiration in Saccharomyces cerevisiae is regulated by small proteins such as the respiratory supercomplex factors (Rcf). One of these factors (Rcf1) has been shown to interact with complexes III (cyt. bc1) and IV (cytochrome c oxidase, CytcO) of the respiratory chain and to modulate the activity of the latter. Here, we investigated the effect of deleting Rcf1 on the functionality of CytcO, purified using a...
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