Article
Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 2016
Rydström Lundin Camilla, von Ballmoos Christoph, Ott Martin, Ädelroth Pia, Brzezinski Peter
Abstract excerpt
The respiratory supercomplex factors (Rcf) 1 and 2 mediate supramolecular interactions between mitochondrial complexes III (ubiquinol-cytochrome c reductase; cyt. bc1) and IV (cytochrome c oxidase; CytcO). In addition, removal of these polypeptides results in decreased activity of CytcO, but not of cyt. bc1 In the present study, we have investigated the kinetics of ligand binding, the single-turnover reaction of...
Topics
- Electron Transport
- Electron Transport Complex III
- Electron Transport Complex IV
- Kinetics
- Mitochondria
- Mutation
- Oxidation-Reduction
- Protein Binding
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Spectrophotometry