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Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant

9 May 2018

Abstract excerpt

Human enteroviruses frequently cause severe diseases in children. Human enteroviruses are transmitted via the fecal-oral route and respiratory droplets, and primary replication occurs in the gastro-intestinal and respiratory tracts; however, how enteroviruses infect these sites is largely unknown. Human intestinal organoids have recently proven to be valuable tools for studying enterovirus-host interactions in...

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PMID: 29743570
DOI: 10.1038/s41426-018-0077-2

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