Article
Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma.
Scientific reports - 8 May 2018
Simbolo Michele, Vicentini Caterina, Ruzzenente Andrea, Brunelli Matteo, Conci Simone, Fassan Matteo, Mafficini Andrea, Rusev Borislav, Corbo Vincenzo, Capelli Paola, Bria Emilio, Pedron Serena, Turri Giona, Lawlor Rita T, Tortora Giampaolo, Bassi Claudio, Guglielmi Alfredo, Scarpa Aldo
Abstract excerpt
The incidence and mortality rates of intrahepatic cholangiocarcinoma have been rising worldwide. Few patients present an early-stage disease that is amenable to curative surgery and after resection, high recurrence rates persist. To identify new independent marker related to aggressive behaviour, two prognostic groups of patient were selected and divided according to prognostic performance. All patients alive at...
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