Article
Keratin 4 regulates the development of human white sponge nevus.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jul 2018
Zhang Jianming, Quan Jingjing, Ren Yongyuan, Chen Mengshan, Yang Jie, Zhang Xu
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the roles of keratin 4 (KRT4) gene in the development of human white sponge nevus (WSN). METHODS: Transgenic mice were created using the microinjection method with pcDNA3.1 vectors expressing KRT4 wild-type (WT) gene and E520K mutation. Polymerase chain reaction (PCR) and Western blotting were used to identify the genotype of transgenic founders and their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.