Article
Malignant transformation of white sponge nevus: a case report of a novel keratin 4 mutation.
BMC oral health - 21 May 2024
Liu Dan, Zhang Tianyu, Zhou Hangfan, Wu Chuanji, Li Taiwen, Jiang Lu
Abstract excerpt
BACKGROUND: White Sponge Nevus (WSN) is traditionally considered a benign genetic disorder affecting the oral mucosa, primarily caused by pathogenic mutations in keratin 4 (KRT4) or keratin 13 (KRT13). Despite its benign nature, recent evidence has begun to question the malignant potential of WSN. CASE PRESENTATION: We report a case involving a 70-year-old man who presented with a white lesion on the right floor...
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