Article
Phenotypical and molecular distinctness of sinonasal haemangiopericytoma compared to solitary fibrous tumour of the sinonasal tract.
Histopathology - 1 Nov 2014
Agaimy Abbas, Barthelmeß Sarah, Geddert Helene, Boltze Carsten, Moskalev Evgeny A, Koch Michael, Wiemann Stefan, Hartmann Arndt, Haller Florian
Abstract excerpt
AIMS: Sinonasal haemangiopericytoma (SN-HPC) is a rare sinonasal mesenchymal neoplasm of perivascular myoid cell origin. Solitary fibrous tumour (SFT) occurs only very rarely in the sinonasal tract. SFT and soft tissue HPC have been considered a single entity. Recently, recurrent gene fusions involving NAB2-STAT6 resulting in differential expression of STAT6 were characterized as central molecular events in SFT....
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