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Cancer Immunotherapy: A Focus on the Regulation of Immune Checkpoints

7 May 2018

Abstract excerpt

In recent years, the role of cancer immunotherapy has become increasingly important compared to traditional cancer treatments, including surgery, chemotherapy and radiotherapy. Of note, the clinical successes of immune checkpoint blockade, such as PD-1 and CTLA-4, represent a landmark event in cancer immunotherapy development. Therefore, further exploration of how immune checkpoints are regulated in the tumor...

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PMID: 29735917
DOI: 10.3390/ijms19051389

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