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PD-1/PD-L1 blockade: Prospectives for immunotherapy in cancer and autoimmunity.

IUBMB life - 1 Nov 2021

Hosseinzadeh Ramin, Feizisani Fahimeh, Shomali Navid, Abdelbasset Walid Kamal, Hemmatzadeh Maryam, Gholizadeh Navashenaq Jamshid, Jadidi-Niaragh Farhad, Bokov Dmitry O, Janebifam Morteza, Mohammadi Hamed

Abstract excerpt

Immune checkpoint blockade therapy (ICBT) has become a successful cancer treatment approach in the field of cancer immunotherapy. Blockade of programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) with monoclonal antibodies have been known as successful examples of cancer immunotherapy in recent years. Although ICBT has been shown to be beneficial in cancers, such benefits have only been seen in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34538007
DOI: 10.1002/iub.2558

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