Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The E2 glycoprotein is necessary but not sufficient for the adaptation of classical swine fever virus lapinized vaccine C-strain to the rabbit.

Virology - 1 Jun 2018

Li Yongfeng, Xie Libao, Zhang Lingkai, Wang Xiao, Li Chao, Han Yuying, Hu Shouping, Sun Yuan, Li Su, Luo Yuzi, Liu Lihong, Munir Muhammad, Qiu Hua-Ji

Abstract excerpt

Classical swine fever virus (CSFV) C-strain was developed through hundreds of passages of a highly virulent CSFV in rabbits. To investigate the molecular basis for the adaptation of C-strain to the rabbit (ACR), a panel of chimeric viruses with the exchange of glycoproteins Erns, E1, and/or E2 between C-strain and the highly virulent Shimen strain and a number of mutant viruses with different amino acid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Biological
Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Classical Swine Fever

Share to Classical Swine Fever Virus

Share to Rabbits

Share to Viral Envelope Proteins

Share to Viral Vaccines

Source

Identifiers

PMID: 29734043
DOI: 10.1016/j.virol.2018.04.016

Genes

ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The E2 glycoprotein is necessary but not sufficient for the adaptation of classical swine fever virus lapinized vaccine C-strain to the rabbit.PMID 29734043Read ↗

The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in SwineSemantic proximity Read ↗

The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge.Semantic proximity Read ↗

Efficacy evaluation of the C-strain-based vaccines against the subgenotype 2.1d classical swine fever virus emerging in China.Semantic proximity Read ↗

Genetic evolution of classical swine fever virus under immune environments conditioned by genotype 1-based modified live virus vaccine.Semantic proximity Read ↗

Antigenic analysis of classical swine fever virus E2 glycoprotein using pig antibodies identifies residues contributing to antigenic variation of the vaccine C-strain and group 2 strains circulating in China.Semantic proximity Read ↗

Classical swine fever in China: a minireview.Semantic proximity Read ↗

Isolation and Characterization of a Moderately Virulent Classical Swine Fever Virus Emerging in China.Semantic proximity Read ↗

In vitro adaptation and genome analysis of a sub-subgenotype 2.1c isolate of classical swine fever virus.Semantic proximity Read ↗

Genotyping and Molecular Characterization of Classical Swine Fever Virus Isolated in China during 2016-2018.Semantic proximity Read ↗

Selection of Classical Swine Fever Virus with Enhanced Pathogenicity Reveals Synergistic Virulence Determinants in E2 and NS4BSemantic proximity Read ↗

N-linked glycosylation status of classical swine fever virus strain Brescia E2 glycoprotein influences virulence in swine.Semantic proximity Read ↗

An attenuated African swine fever virus expressing the E2 glycoprotein of classical swine fever virus protects pigs against challenge of both virusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.