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Article

Genetic evolution of classical swine fever virus under immune environments conditioned by genotype 1-based modified live virus vaccine.

Transboundary and emerging diseases - 1 Jun 2018

Yoo S J, Kwon T, Kang K, Kim H, Kang S C, Richt J A, Lyoo Y S

Abstract excerpt

Modified live vaccines (MLVs) based on genotype 1 strains, particularly C-strain, have been used to prevent and control classical swine fever virus (CSFV) worldwide. Nevertheless, a shift in the predominant CSFV strains circulating in the field from genotype 1 or 3 to genotype 2 is seen. Genotype 2 is genetically distant from the vaccine strains and was recently reported during outbreaks after vaccine failure;...

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PMID: 29319233
DOI: 10.1111/tbed.12798

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