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Article

Leu600 mutations decrease product inhibition of the β-cyclodextrin glycosyltransferase from Bacillus circulans STB01.

International journal of biological macromolecules - 1 Aug 2018

Chen Shuangdi, Li Zhaofeng, Gu Zhengbiao, Hong Yan, Cheng Li, Holler Tod P, Li Caiming

Abstract excerpt

The limits that cyclodextrin products impose on their industrial production from starch by cyclodextrin glycosyltransferases (CGTases) are a severe problem. In this paper, mutants at residue Leu600 of the β-CGTase from Bacillus circulans STB01 were constructed in an effort to decrease the product inhibition exhibited by β-cyclodextrin. A kinetic analysis of the inhibition of the wild-type and mutant β-CGTases by...

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PMID: 29733932
DOI: 10.1016/j.ijbiomac.2018.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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