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Article

CRISPR/Cas9 Gene editing of RyR2 in human stem cell-derived cardiomyocytes provides a novel approach in investigating dysfunctional Ca2+ signaling

27 Apr 2018

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 29730419
DOI: 10.1016/j.ceca.2018.04.009

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CRISPR/Cas9 Gene editing of RyR2 in human stem cell-derived cardiomyocytes provides a novel approach in investigating dysfunctional Ca2+ signalingPMID 29730419Read ↗

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Calcium signaling consequences of RyR2 mutations associated with CPVT1 introduced via CRISPR/Cas9 gene editing in human-induced pluripotent stem cell-derived cardiomyocytes: Comparison of RyR2-R420Q, F2483I, and Q4201R.Semantic proximity Read ↗

Attempts to Create Transgenic Mice Carrying the Q3924E Mutation in RyR2 Ca2+ Binding Site.Semantic proximity Read ↗

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The Role of RyR2 Mutations in Congenital Heart Diseases: Insights Into Cardiac Electrophysiological Mechanisms.Semantic proximity Read ↗

CRISPR/CAS9: A promising approach for the research and treatment of cardiovascular diseasesSemantic proximity Read ↗

Characterisation of the mechanism by which a nonsense variant in <i>RYR2</i> results in ventricular arrhythmiaSemantic proximity Read ↗

Do CPVT-linked mutations alter RYR2 regulation by cytosolic Ca2+ in cardiomyocytes?Semantic proximity Read ↗

A CRISPR/Cas9 strategy for the generation of a FLNC knockout hESC line (WAe009-A-70) to model dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy.Semantic proximity Read ↗

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