Article
The role of calcium channel mutations in human epilepsy.
Progress in brain research - 1 Jan 2014
Gambardella Antonio, Labate Angelo
Abstract excerpt
Molecular insights into monogenic idiopathic epilepsies have illustrated the central role of channelopathies in their etiology. Among ion channels, both high- and low-voltage-activated calcium channels and their ancillary subunits Cav2.1 (P/Q-type) calcium channels support a number of dynamic processes in neurons at both presynaptic and postsynaptic levels being critical determinants of neuronal excitability....
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