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CCNG2 Overexpression Mediated by AKT Inhibits Tumor Cell Proliferation in Human Astrocytoma Cells

18 Apr 2018

Abstract excerpt

The cyclin family protein CCNG2 has an important inhibitory role in cancer initiation and progression but the exact mechanism is still unknown. In the present study, we examined the relationship between CCNG2 and the malignancy of astrocytomas and whether the AKT pathway, which is upregulated in astrocytomas, may inhibit CCNG2 expression. CCNG2 expression was found to be negatively associated with the...

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PMID: 29720957
DOI: 10.3389/fneur.2018.00255

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