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Article

AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion

27 May 2010

Abstract excerpt

Recent data suggest that AKT2, one of AKT isoforms, plays an important role in tumorigenesis of human cancers. However, little evidence exists to show the mechanism of AKT2 involved in tumorigenesis. In this study, we show that AKT2 protein expression increased significantly in high grade gliomas in comparison to low grade gliomas and correlated with the expression of NFkappaB, BCL2, MMP2 and MMP9 by...

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PMID: 20514445
DOI: 10.3892/or_00000829

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