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Article

Perturbing the acetylation status of the Type IV pilus retraction motor, PilT, reduces Neisseria gonorrhoeae viability.

Molecular microbiology - 1 Dec 2018

Hockenberry Alyson M, Post Deborah M B, Rhodes Katherine A, Apicella Michael, So Magdalene

Abstract excerpt

Post-translational acetylation is a common protein modification in bacteria. It was recently reported that Neisseria gonorrhoeae acetylates the Type IV pilus retraction motor, PilT. Here, we show recombinant PilT can be acetylated in vitro and acetylation does not affect PilT ultrastructure. To investigate the function of PilT acetylation, we mutated an acetylated lysine, K117, to mimic its acetylated or...

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Source

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Identifiers

PMID: 29719082
DOI: 10.1111/mmi.13979
PMCID: PMC6214798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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