Article
Pilus-mediated adhesion of Neisseria meningitidis is negatively controlled by the pilus-retraction machinery.
Molecular microbiology - 1 Jan 2006
Yasukawa Kazutoyo, Martin Patricia, Tinsley Colin R, Nassif Xavier
Abstract excerpt
The type IV pili (Tfp) of Neisseria meningitidis play an essential role in meningococcal virulence by mediating the initial interaction of bacteria with host cells. Tfp are also subject to retraction, which relies on the PilT protein. Among the other components of the Tfp machinery, PilC1, a pilus-associated protein, is important for Tfp biogenesis and adhesion. Adhesion of N. meningitidis to living epithelial...
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