Article
Genome-wide copy number variant analysis reveals variants associated with 10 diverse production traits in Holstein cattle.
BMC genomics - 2 May 2018
Zhou Yang, Connor Erin E, Wiggans George R, Lu Yongfang, Tempelman Robert J, Schroeder Steven G, Chen Hong, Liu George E
Abstract excerpt
BACKGROUND: Copy number variation (CNV) is an important type of genetic variation contributing to phenotypic differences among mammals and may serve as an alternative molecular marker to single nucleotide polymorphism (SNP) for genome-wide association study (GWAS). Recently, GWAS analysis using CNV has been applied in livestock, although few studies have focused on Holstein cattle. RESULTS: We describe 191 CNV...
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