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Analysis of copy number variations in Holstein cows identify potential mechanisms contributing to differences in residual feed intake.

Functional & integrative genomics - 1 Nov 2012

Hou Yali, Bickhart Derek M, Chung Hoyoung, Hutchison Jana L, Norman H Duane, Connor Erin E, Liu George E

Abstract excerpt

Genomic structural variation is an important and abundant source of genetic and phenotypic variation. In this study, we performed an initial analysis of copy number variations (CNVs) using BovineHD SNP genotyping data from 147 Holstein cows identified as having high or low feed efficiency as estimated by residual feed intake (RFI). We detected 443 candidate CNV regions (CNVRs) that represent 18.4 Mb (0.6 %) of...

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PMID: 22991089
DOI: 10.1007/s10142-012-0295-y

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