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Genome-wide association analyses reveal copy number variant regions associated with reproduction and disease traits in Canadian Holstein cattle.

Journal of dairy science - 1 Sept 2024

Rojas de Oliveira Hinayah, Chud Tatiane C S, Oliveira Gerson A, Hermisdorff Isis C, Narayana Saranya G, Rochus Christina M, Butty Adrien M, Malchiodi Francesca, Stothard Paul, Miglior Filippo, Baes Christine F, Schenkel Flavio S

Abstract excerpt

This study aimed to evaluate the impact of copy number variants (CNV) on 13 reproduction and 12 disease traits in Holstein cattle. Intensity signal files containing log R ratio and B allele frequency information from 13,730 Holstein animals genotyped with a 95K SNP panel, and 8,467 Holstein animals genotyped with a 50K SNP panel were used to identify the CNVs. Subsequently, the identified CNVs were validated...

Topics

Animals
Cattle
Genome-Wide Association Study
Reproduction
DNA Copy Number Variations
Polymorphism, Single Nucleotide
Genotype
Cattle Diseases
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Canada

Gene Frequency

Source

Identifiers

PMID: 38788846
DOI: 10.3168/jds.2023-24295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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