Article
Discovery and description of a new serogroup 7 Streptococcus pneumoniae serotype, 7D, and structural analysis of 7C and 7D.
Carbohydrate research - 30 Jun 2018
Kjeldsen Christian, Slott Sofie, Elverdal Pernille L, Sheppard Carmen L, Kapatai Georgia, Fry Norman K, Skovsted Ian C, Duus Jens Ø
Abstract excerpt
Streptococcus pneumoniae is characterised into 92 serotypes based on antigenic reactions of commercial rabbit sera to the capsular polysaccharides. During development of a bioinformatic serotyping tool (PneumoCaT), an isolate exhibited a novel codon at residue 385 of the glycosyltransferase gene wcwK encoding a distinct amino acid, which differentiates genogroup 7. Investigation by repeat serotyping and Quellung...
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