Article
Genomics Reveals the Worldwide Distribution of Multidrug-Resistant Serotype 6E Pneumococci.
Journal of clinical microbiology - 1 Jul 2015
van Tonder Andries J, Bray James E, Roalfe Lucy, White Rebecca, Zancolli Marta, Quirk Sigríður J, Haraldsson Gunnsteinn, Jolley Keith A, Maiden Martin C J, Bentley Stephen D, Haraldsson Ásgeir, Erlendsdóttir Helga, Kristinsson Karl G, Goldblatt David, Brueggemann Angela B
Abstract excerpt
The pneumococcus is a leading pathogen infecting children and adults. Safe, effective vaccines exist, and they work by inducing antibodies to the polysaccharide capsule (unique for each serotype) that surrounds the cell; however, current vaccines are limited by the fact that only a few of the nearly 100 antigenically distinct serotypes are included in the formulations. Within the serotypes, serogroup 6...
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