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Article

Novel Mutations Associated with Clofazimine Resistance in Mycobacterium abscessus.

Antimicrobial agents and chemotherapy - 1 Jul 2018

Chen Yuanyuan, Chen Jiazhen, Zhang Shuo, Shi Wanliang, Zhang Wenhong, Zhu Min, Zhang Ying

Abstract excerpt

Mycobacterium abscessus is a major nontuberculous mycobacterial (NTM) pathogen and is responsible for about 80% of all pulmonary infections caused by rapidly growing mycobacteria. Clofazimine is an effective drug active against M. abscessus, but the mechanism of resistance to clofazimine in M. abscessus is unknown. To investigate the molecular basis of clofazimine resistance in M. abscessus, we isolated 29 M....

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Identifiers

PMID: 29712660
DOI: 10.1128/AAC.00544-18
PMCID: PMC6021651

Genes

NTM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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