Article
Influence of SNPs in Genes that Modulate Lung Disease Severity in a Group of Mexican Patients with Cystic Fibrosis.
Archives of medical research - 1 Jan 2018
Yokoyama Emiy, Chávez-Saldaña Margarita, Orozco Lorena, Cuevas Francisco, Lezana José Luis, Vigueras-Villaseñor Rosa María, Rojas-Castañeda Julio Cesar, Landero Daniel Adrian
Abstract excerpt
BACKGROUND: The variation in cystic fibrosis (CF) lung disease not always is explained by the CFTR genotype, so it has become apparent that modifier genes must play a considerable role in the phenotypic heterogeneity of CF, so we investigated the association of allelic variants in modifier genes that modulate the severity of lung function in a group of Mexican patients diagnosed with CF. METHODS: We included 140...
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