Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Premyogenic progenitors derived from human pluripotent stem cells expand in floating culture and differentiate into transplantable myogenic progenitors

20 Apr 2018

Abstract excerpt

Abstract Human induced pluripotent stem cells (hiPSCs) are a potential source for cell therapy of Duchenne muscular dystrophy. To reliably obtain skeletal muscle progenitors from hiPSCs, we treated hiPS cells with a Wnt activator, CHIR-99021 and a BMP receptor inhibitor, LDN-193189, and then induced skeletal muscle cells using a previously reported sphere-based culture. This protocol greatly improved sphere...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Muscle Physiology and Disorders
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29700358
DOI: 10.1038/s41598-018-24959-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Premyogenic progenitors derived from human pluripotent stem cells expand in floating culture and differentiate into transplantable myogenic progenitorsPMID 29700358Read ↗

Core Transcription Factors Promote Induction of PAX3-Positive Skeletal Muscle Stem CellsSemantic proximity Read ↗

Directed Differentiation of Human Pluripotent Stem Cells toward Skeletal Myogenic Progenitors and Their Purification Using Surface MarkersSemantic proximity Read ↗

Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cellsSemantic proximity Read ↗

Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem CellsSemantic proximity Read ↗

Single-cell RNA-seq reveals heterogeneity in hiPSC-derived muscle progenitors and E2F family as a key regulator of proliferationSemantic proximity Read ↗

Characterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell TherapySemantic proximity Read ↗

Multilineage Differentiation for Formation of Innervated Skeletal Muscle Fibers from Healthy and Diseased Human Pluripotent Stem CellsSemantic proximity Read ↗

Generation of Skeletal Muscle Organoids from Human Pluripotent Stem CellsSemantic proximity Read ↗

Human iPS Cells Derived Skeletal Muscle Progenitor Cells Promote Myoangiogenesis and Restore Dystrophin in Duchenne Muscular Dystrophic MiceSemantic proximity Read ↗

Induction of Skeletal Muscle Progenitors and Stem Cells from human induced Pluripotent Stem CellsSemantic proximity Read ↗

iPSC-derived skeletal muscle spheroids for Duchenne Muscular Dystrophy modelingSemantic proximity Read ↗

Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.