Article
Opportunities and Challenges in Cardiovascular Pharmacogenomics: From Discovery to Implementation.
Circulation research - 27 Apr 2018
Roden Dan M, Van Driest Sara L, Wells Quinn S, Mosley Jonathan D, Denny Joshua C, Peterson Josh F
Abstract excerpt
This review will provide an overview of the principles of pharmacogenomics from basic discovery to implementation, encompassing application of tools of contemporary genome science to the field (including areas of apparent divergence from disease-based genomics), a summary of lessons learned from the extensively studied drugs clopidogrel and warfarin, the current status of implementing pharmacogenetic testing in...
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