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Article

Pharmacogenetics and cardiovascular disease--implications for personalized medicine.

Pharmacological reviews - 1 Jul 2013

Johnson Julie A, Cavallari Larisa H

Abstract excerpt

The past decade has seen tremendous advances in our understanding of the genetic factors influencing response to a variety of drugs, including those targeted at treatment of cardiovascular diseases. In the case of clopidogrel, warfarin, and statins, the literature has become sufficiently strong that guidelines are now available describing the use of genetic information to guide treatment with these therapies, and...

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Identifiers

PMID: 23686351
DOI: 10.1124/pr.112.007252
PMCID: PMC3698938

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VKORC1

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