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Article

The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda.

Virology journal - 27 Apr 2018

Nanteza Mary Bridget, Bakamutumaho Barnabas, Kisakye Annet, Namuwulya Prossy, Bukenya Henry, Katushabe Edson, Bwogi Josephine, Byabamazima Charles Rutebarika, Williams Raffaella, Gumede Nicksy

Abstract excerpt

BACKGROUND: The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs). METHODS: In 2014, two VDPVs type 2 were identified during routine surveillance of acute flaccid paralysis (AFP) cases. Consequently, a retrospective VDPV survey was conducted to ensure that there was no circulating VDPV in the country. All Sabin poliovirus isolates identified in...

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Identifiers

PMID: 29699577
DOI: 10.1186/s12985-018-0990-y
PMCID: PMC5922010

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AFP

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