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Article

Mapping genetic variants for cranial vault shape in humans.

PloS one - 1 Jan 2018

Roosenboom Jasmien, Lee Myoung Keun, Hecht Jacqueline T, Heike Carrie L, Wehby George L, Christensen Kaare, Feingold Eleanor, Marazita Mary L, Maga A Murat, Shaffer John R, Weinberg Seth M

Abstract excerpt

The shape of the cranial vault, a region comprising interlocking flat bones surrounding the cerebral cortex, varies considerably in humans. Strongly influenced by brain size and shape, cranial vault morphology has both clinical and evolutionary relevance. However, little is known about the genetic basis of normal vault shape in humans. We performed a genome-wide association study (GWAS) on three vault measures...

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Identifiers

PMID: 29698431
DOI: 10.1371/journal.pone.0196148
PMCID: PMC5919379

Genes

NLK
SOX11
SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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