Article
Admixture Mapping Links RACGAP1 Regulation to Prostate Cancer in African Americans.
Cancer genomics & proteomics - 1 Jan 2000
Wilson Bradford D, Ricks-Santi Luisel J, Mason Tshela E, Abbas Muneer, Kittles Rick A, Dunston Georgia M, Kanaan Yasmine M
Abstract excerpt
BACKGROUND/AIM: Prostate cancer is the most common malignancy in US males. African American men have higher incidence and mortality rates than European Americans. Five single nucleotide polymorphisms are associated with PCa. We hypothesized haplotypes inferred from these SNPs are also associated with PCa. PATIENTS AND METHODS: We genotyped SNPs in a case-control admixture mapping study. SNP haplotypes inferred...
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