Article
Identification of genetic risk associated with prostate cancer using ancestry informative markers.
Prostate cancer and prostatic diseases - 1 Dec 2012
Ricks-Santi L J, Apprey V, Mason T, Wilson B, Abbas M, Hernandez W, Hooker S, Doura M, Bonney G, Dunston G, Kittles R, Ahaghotu C
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) is a common malignancy and a leading cause of cancer death among men in the United States with African-American (AA) men having the highest incidence and mortality rates. Given recent results from admixture mapping and genome-wide association studies for PCa in AA men, it is clear that many risk alleles are enriched in men with West African genetic ancestry. METHODS: A total of...
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